Predictive performance, inclusive PGS

Predictive performance of inclusive PGS model in the hMG study

Trait name	Target Trait type	PGS Trait type	Population	Model	Metric	Predictive Performance	95% CI	P-value
Trait name	Target Trait type	PGS Trait type	Population	Model	Metric	Predictive Performance	95% CI	P-value

BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Covariate-only model	AUROC	0.646	[0.640, 0.653]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.634	[0.628, 0.641]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.652	[0.646, 0.659]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	AUROC	0.643	[0.637, 0.650]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.649	[0.642, 0.656]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.650	[0.644, 0.657]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	AUROC	0.707	[0.701, 0.713]	<1.0x10^-300
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Covariate-only model	AUROC	0.671	[0.640, 0.701]	6.4x10^-24
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.623	[0.592, 0.654]	3.4x10^-14
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.642	[0.611, 0.672]	1.6x10^-17
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	AUROC	0.644	[0.613, 0.674]	1.1x10^-16
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.672	[0.642, 0.703]	2.6x10^-24
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.674	[0.643, 0.704]	1.7x10^-24
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	AUROC	0.723	[0.694, 0.751]	1.7x10^-36
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Covariate-only model	AUROC	0.600	[0.540, 0.660]	7.8x10^-04
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.660	[0.602, 0.718]	1.4x10^-07
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.681	[0.624, 0.737]	2.5x10^-08
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	AUROC	0.661	[0.601, 0.720]	3.7x10^-07
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.601	[0.541, 0.661]	8.6x10^-04
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.602	[0.542, 0.662]	7.9x10^-04
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	AUROC	0.675	[0.616, 0.734]	7.9x10^-09
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Covariate-only model	AUROC	0.615	[0.566, 0.664]	7.9x10^-06
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Genotype-only model	AUROC	0.561	[0.512, 0.609]	1.7x10^-02
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Genotype-only model	AUROC	0.590	[0.541, 0.638]	6.9x10^-04
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	AUROC	0.605	[0.557, 0.653]	1.0x10^-04
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.616	[0.567, 0.665]	7.1x10^-06
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.617	[0.568, 0.665]	6.5x10^-06
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	AUROC	0.649	[0.601, 0.696]	1.0x10^-08
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Covariate-only model	AUROC	0.670	[0.651, 0.688]	2.9x10^-64
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.599	[0.580, 0.618]	9.9x10^-23
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.622	[0.603, 0.641]	1.4x10^-32
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	AUROC	0.623	[0.604, 0.642]	4.4x10^-33
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.670	[0.652, 0.689]	1.1x10^-64
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.671	[0.653, 0.690]	4.7x10^-65
BLQ: PLs in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	AUROC	0.709	[0.691, 0.726]	1.0x10^-87
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Covariate-only model	AUROC	0.647	[0.640, 0.654]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.637	[0.630, 0.644]	1.6x10^-292
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.656	[0.649, 0.663]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	AUROC	0.642	[0.635, 0.649]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.649	[0.642, 0.656]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.650	[0.643, 0.657]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	AUROC	0.705	[0.698, 0.712]	<1.0x10^-300
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Covariate-only model	AUROC	0.674	[0.642, 0.706]	1.4x10^-21
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.633	[0.600, 0.665]	1.2x10^-13
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.640	[0.608, 0.672]	1.1x10^-14
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	AUROC	0.627	[0.595, 0.658]	1.3x10^-12
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.676	[0.644, 0.708]	7.6x10^-22
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.677	[0.645, 0.708]	6.0x10^-22
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	AUROC	0.718	[0.688, 0.749]	1.8x10^-31
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Covariate-only model	AUROC	0.563	[0.496, 0.631]	6.4x10^-02
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.659	[0.595, 0.723]	3.2x10^-06
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.665	[0.601, 0.728]	5.5x10^-06
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	AUROC	0.646	[0.582, 0.710]	1.5x10^-05
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.565	[0.498, 0.632]	6.8x10^-02
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.566	[0.499, 0.633]	6.7x10^-02
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	AUROC	0.627	[0.560, 0.694]	7.9x10^-05
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Covariate-only model	AUROC	0.624	[0.578, 0.671]	6.2x10^-07
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Genotype-only model	AUROC	0.585	[0.538, 0.631]	2.1x10^-04
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Genotype-only model	AUROC	0.593	[0.547, 0.639]	9.0x10^-05
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	AUROC	0.581	[0.535, 0.628]	1.1x10^-03
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.625	[0.579, 0.671]	5.4x10^-07
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.625	[0.579, 0.672]	5.1x10^-07
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	AUROC	0.642	[0.597, 0.688]	5.4x10^-09
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Covariate-only model	AUROC	0.670	[0.651, 0.690]	4.0x10^-57
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.606	[0.586, 0.626]	3.8x10^-23
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.620	[0.600, 0.640]	1.2x10^-29
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	AUROC	0.617	[0.597, 0.638]	4.1x10^-27
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.671	[0.651, 0.690]	6.1x10^-57
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.671	[0.652, 0.690]	3.6x10^-57
BLQ: CE in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	AUROC	0.704	[0.685, 0.723]	2.8x10^-77
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Covariate-only model	AUROC	0.638	[0.632, 0.645]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.633	[0.627, 0.640]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.652	[0.645, 0.658]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	AUROC	0.642	[0.635, 0.648]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.640	[0.633, 0.646]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.641	[0.634, 0.647]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	AUROC	0.701	[0.695, 0.707]	<1.0x10^-300
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Covariate-only model	AUROC	0.660	[0.629, 0.690]	2.8x10^-22
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.629	[0.599, 0.659]	4.9x10^-16
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.644	[0.614, 0.674]	1.1x10^-18
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	AUROC	0.647	[0.617, 0.677]	2.3x10^-18
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.661	[0.631, 0.692]	1.5x10^-22
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.662	[0.632, 0.693]	1.1x10^-22
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	AUROC	0.718	[0.690, 0.745]	1.1x10^-36
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Covariate-only model	AUROC	0.580	[0.524, 0.636]	3.2x10^-03
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.637	[0.582, 0.693]	7.0x10^-07
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.657	[0.604, 0.710]	1.0x10^-07
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	AUROC	0.629	[0.573, 0.685]	4.2x10^-06
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.580	[0.524, 0.636]	3.4x10^-03
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.581	[0.525, 0.637]	3.2x10^-03
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	AUROC	0.640	[0.582, 0.697]	2.6x10^-07
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Covariate-only model	AUROC	0.604	[0.553, 0.655]	8.6x10^-05
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Genotype-only model	AUROC	0.559	[0.509, 0.608]	3.3x10^-02
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Genotype-only model	AUROC	0.594	[0.545, 0.643]	6.7x10^-04
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	AUROC	0.593	[0.544, 0.642]	4.3x10^-04
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.604	[0.554, 0.655]	8.0x10^-05
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.605	[0.554, 0.655]	7.5x10^-05
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	AUROC	0.634	[0.585, 0.684]	2.7x10^-07
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Covariate-only model	AUROC	0.656	[0.638, 0.674]	4.8x10^-58
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.601	[0.582, 0.620]	1.4x10^-25
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.624	[0.605, 0.642]	1.3x10^-35
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	AUROC	0.624	[0.606, 0.643]	8.6x10^-35
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.656	[0.637, 0.674]	8.6x10^-58
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.656	[0.638, 0.675]	4.3x10^-58
BLQ: Free Chol. in CMs and XXL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	AUROC	0.696	[0.679, 0.714]	1.2x10^-83
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Covariate-only model	AUROC	0.669	[0.660, 0.678]	2.4x10^-279
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.649	[0.640, 0.658]	1.0x10^-213
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.664	[0.655, 0.673]	1.5x10^-258
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	AUROC	0.637	[0.628, 0.646]	3.9x10^-182
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.671	[0.662, 0.680]	2.9x10^-285
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.672	[0.663, 0.681]	5.3x10^-287
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	AUROC	0.718	[0.710, 0.727]	<1.0x10^-300
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Covariate-only model	AUROC	0.716	[0.679, 0.754]	8.8x10^-22
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.641	[0.601, 0.681]	1.6x10^-11
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.649	[0.610, 0.688]	3.2x10^-12
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	AUROC	0.611	[0.571, 0.652]	4.3x10^-08
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.718	[0.681, 0.755]	5.1x10^-22
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.718	[0.681, 0.755]	4.4x10^-22
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	AUROC	0.748	[0.713, 0.784]	9.4x10^-27
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Covariate-only model	AUROC	0.641	[0.565, 0.717]	6.5x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.652	[0.572, 0.733]	3.2x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.665	[0.583, 0.747]	1.1x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	AUROC	0.620	[0.541, 0.699]	2.4x10^-03
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.641	[0.565, 0.717]	6.6x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.642	[0.566, 0.718]	6.4x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	AUROC	0.676	[0.595, 0.757]	8.9x10^-06
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Covariate-only model	AUROC	0.623	[0.576, 0.669]	6.2x10^-07
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Genotype-only model	AUROC	0.566	[0.518, 0.614]	5.9x10^-03
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Genotype-only model	AUROC	0.586	[0.539, 0.634]	4.0x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	AUROC	0.586	[0.539, 0.634]	7.7x10^-04
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.621	[0.575, 0.668]	7.6x10^-07
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.622	[0.575, 0.668]	7.2x10^-07
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	AUROC	0.645	[0.599, 0.690]	4.4x10^-09
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Covariate-only model	AUROC	0.692	[0.668, 0.716]	4.6x10^-51
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.609	[0.584, 0.634]	3.5x10^-17
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.625	[0.600, 0.649]	5.8x10^-22
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	AUROC	0.620	[0.595, 0.645]	2.3x10^-20
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.692	[0.669, 0.716]	1.2x10^-49
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.693	[0.669, 0.717]	8.2x10^-50
BLQ: PLs in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	AUROC	0.716	[0.693, 0.739]	1.3x10^-60
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Covariate-only model	AUROC	0.654	[0.646, 0.661]	<1.0x10^-300
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.640	[0.633, 0.648]	1.3x10^-273
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.659	[0.651, 0.666]	<1.0x10^-300
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	AUROC	0.639	[0.632, 0.647]	3.0x10^-271
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.655	[0.648, 0.663]	<1.0x10^-300
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.656	[0.648, 0.663]	<1.0x10^-300
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	AUROC	0.708	[0.701, 0.715]	<1.0x10^-300
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Covariate-only model	AUROC	0.693	[0.658, 0.727]	1.4x10^-25
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.630	[0.596, 0.664]	1.0x10^-12
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.649	[0.616, 0.682]	1.5x10^-15
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	AUROC	0.638	[0.604, 0.671]	5.0x10^-14
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.694	[0.660, 0.728]	7.3x10^-26
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.694	[0.660, 0.728]	6.1x10^-26
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	AUROC	0.739	[0.707, 0.771]	2.6x10^-35
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Covariate-only model	AUROC	0.636	[0.576, 0.696]	4.2x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.637	[0.575, 0.699]	3.6x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.641	[0.578, 0.704]	2.0x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	AUROC	0.623	[0.560, 0.685]	6.1x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.637	[0.577, 0.697]	3.5x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.637	[0.577, 0.697]	3.4x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	AUROC	0.669	[0.606, 0.733]	3.8x10^-08
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Covariate-only model	AUROC	0.625	[0.579, 0.671]	3.6x10^-07
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Genotype-only model	AUROC	0.583	[0.536, 0.630]	5.7x10^-04
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Genotype-only model	AUROC	0.602	[0.555, 0.648]	1.3x10^-05
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	AUROC	0.604	[0.557, 0.650]	7.8x10^-06
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.625	[0.578, 0.671]	3.9x10^-07
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.625	[0.579, 0.671]	3.7x10^-07
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	AUROC	0.658	[0.613, 0.703]	1.5x10^-10
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Covariate-only model	AUROC	0.682	[0.662, 0.702]	7.2x10^-61
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.597	[0.576, 0.618]	1.2x10^-18
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.621	[0.600, 0.643]	8.1x10^-28
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	AUROC	0.610	[0.589, 0.632]	1.7x10^-23
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.682	[0.662, 0.702]	6.5x10^-61
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.682	[0.662, 0.702]	4.5x10^-61
BLQ: Free Chol. in XL VLDL	BLQ (binarized at BLQ threshold)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	AUROC	0.706	[0.686, 0.726]	1.8x10^-73
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Covariate-only model	AUROC	0.637	[0.630, 0.644]	1.9x10^-288
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.515	[0.508, 0.523]	6.5x10^-05
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.590	[0.583, 0.597]	4.1x10^-124
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Genotype-only model	AUROC	0.626	[0.618, 0.633]	4.5x10^-238
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.617	[0.609, 0.624]	9.8x10^-198
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.651	[0.644, 0.658]	<1.0x10^-300
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Full model (covariates and genotypes)	AUROC	0.687	[0.680, 0.694]	<1.0x10^-300
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Covariate-only model	AUROC	0.675	[0.642, 0.708]	6.3x10^-23
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.523	[0.488, 0.558]	1.9x10^-01
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.592	[0.558, 0.626]	1.2x10^-07
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Genotype-only model	AUROC	0.622	[0.589, 0.654]	2.9x10^-11
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.654	[0.621, 0.688]	7.5x10^-18
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.674	[0.642, 0.707]	8.3x10^-23
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	AUROC	0.718	[0.687, 0.748]	3.2x10^-31
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Covariate-only model	AUROC	0.599	[0.536, 0.662]	8.5x10^-04
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.532	[0.468, 0.596]	2.7x10^-01
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.612	[0.553, 0.672]	2.8x10^-04
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Genotype-only model	AUROC	0.657	[0.596, 0.718]	7.9x10^-07
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.614	[0.553, 0.675]	7.2x10^-04
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.657	[0.597, 0.717]	1.2x10^-06
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	AUROC	0.673	[0.611, 0.735]	2.8x10^-08
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Covariate-only model	AUROC	0.576	[0.529, 0.623]	3.0x10^-03
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	AUROC	0.516	[0.468, 0.563]	4.5x10^-01
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	AUROC	0.553	[0.505, 0.600]	3.2x10^-02
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Genotype-only model	AUROC	0.573	[0.526, 0.620]	1.3x10^-02
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.568	[0.521, 0.615]	4.6x10^-03
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.587	[0.541, 0.634]	5.8x10^-04
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Full model (covariates and genotypes)	AUROC	0.594	[0.548, 0.641]	1.5x10^-04
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Covariate-only model	AUROC	0.661	[0.641, 0.681]	3.8x10^-51
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.517	[0.496, 0.538]	3.5x10^-02
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.586	[0.565, 0.607]	4.7x10^-16
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Genotype-only model	AUROC	0.610	[0.590, 0.631]	6.2x10^-24
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.651	[0.631, 0.671]	1.8x10^-42
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.669	[0.649, 0.689]	1.0x10^-53
BLQ: PLs to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Full model (covariates and genotypes)	AUROC	0.695	[0.676, 0.714]	9.1x10^-68
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Covariate-only model	AUROC	0.639	[0.631, 0.647]	2.0x10^-242
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.458	[0.449, 0.466]	1.3x10^-25
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.469	[0.461, 0.478]	9.6x10^-15
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Genotype-only model	AUROC	0.629	[0.621, 0.637]	3.4x10^-215
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.519	[0.510, 0.527]	5.6x10^-05
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.524	[0.516, 0.533]	1.0x10^-07
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Full model (covariates and genotypes)	AUROC	0.689	[0.681, 0.696]	<1.0x10^-300
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Covariate-only model	AUROC	0.688	[0.653, 0.722]	2.1x10^-21
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.473	[0.434, 0.511]	1.3x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.493	[0.454, 0.533]	7.1x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Genotype-only model	AUROC	0.611	[0.577, 0.646]	5.5x10^-09
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.554	[0.514, 0.593]	5.0x10^-03
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.567	[0.527, 0.606]	3.6x10^-04
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	AUROC	0.722	[0.689, 0.754]	6.6x10^-28
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Covariate-only model	AUROC	0.562	[0.490, 0.634]	7.1x10^-02
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.469	[0.400, 0.537]	3.4x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.475	[0.403, 0.546]	4.7x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Genotype-only model	AUROC	0.660	[0.594, 0.725]	1.6x10^-06
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.500	[0.433, 0.567]	9.8x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.509	[0.439, 0.578]	9.0x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	AUROC	0.630	[0.561, 0.700]	5.4x10^-05
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Covariate-only model	AUROC	0.598	[0.550, 0.646]	2.3x10^-04
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	AUROC	0.478	[0.428, 0.527]	3.8x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	AUROC	0.481	[0.431, 0.531]	6.0x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Genotype-only model	AUROC	0.551	[0.501, 0.600]	5.2x10^-02
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.529	[0.480, 0.579]	2.0x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.525	[0.475, 0.575]	1.8x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Full model (covariates and genotypes)	AUROC	0.606	[0.558, 0.654]	3.5x10^-05
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Covariate-only model	AUROC	0.665	[0.644, 0.686]	3.1x10^-45
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.472	[0.449, 0.495]	1.8x10^-02
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.481	[0.458, 0.505]	1.4x10^-01
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Genotype-only model	AUROC	0.608	[0.586, 0.630]	1.0x10^-20
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.551	[0.528, 0.574]	6.7x10^-06
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.555	[0.532, 0.578]	1.6x10^-06
BLQ: CE to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Full model (covariates and genotypes)	AUROC	0.693	[0.673, 0.713]	7.8x10^-60
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Covariate-only model	AUROC	0.627	[0.620, 0.634]	8.2x10^-274
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.455	[0.448, 0.462]	6.3x10^-36
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.441	[0.434, 0.448]	1.4x10^-62
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Genotype-only model	AUROC	0.625	[0.618, 0.632]	1.6x10^-249
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.570	[0.563, 0.578]	1.2x10^-76
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.520	[0.512, 0.527]	5.3x10^-06
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	White British	Full model (covariates and genotypes)	AUROC	0.679	[0.673, 0.686]	<1.0x10^-300
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Covariate-only model	AUROC	0.661	[0.629, 0.694]	3.3x10^-21
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.465	[0.431, 0.499]	2.8x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.440	[0.407, 0.473]	7.6x10^-04
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Genotype-only model	AUROC	0.621	[0.590, 0.653]	2.1x10^-12
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.610	[0.576, 0.644]	8.7x10^-10
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.547	[0.512, 0.581]	6.3x10^-03
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	AUROC	0.706	[0.676, 0.737]	1.4x10^-30
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Covariate-only model	AUROC	0.577	[0.519, 0.636]	4.1x10^-03
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.490	[0.433, 0.548]	5.5x10^-01
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.483	[0.424, 0.542]	5.1x10^-01
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Genotype-only model	AUROC	0.620	[0.562, 0.677]	1.5x10^-05
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.557	[0.500, 0.613]	4.7x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.537	[0.479, 0.595]	2.2x10^-01
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	AUROC	0.631	[0.570, 0.691]	1.0x10^-06
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Covariate-only model	AUROC	0.560	[0.513, 0.608]	1.7x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	AUROC	0.515	[0.467, 0.562]	3.9x10^-01
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	AUROC	0.507	[0.460, 0.555]	4.3x10^-01
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Genotype-only model	AUROC	0.558	[0.511, 0.606]	4.2x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.558	[0.510, 0.605]	1.3x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.548	[0.501, 0.595]	3.3x10^-02
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	African	Full model (covariates and genotypes)	AUROC	0.577	[0.530, 0.623]	1.8x10^-03
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Covariate-only model	AUROC	0.644	[0.624, 0.663]	1.4x10^-44
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.467	[0.447, 0.487]	2.0x10^-03
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.460	[0.439, 0.480]	1.4x10^-04
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Genotype-only model	AUROC	0.608	[0.589, 0.628]	1.4x10^-24
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.603	[0.583, 0.623]	6.8x10^-23
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.559	[0.538, 0.580]	1.1x10^-08
BLQ: Free Chol. to Tot. Lipids in CMs and XXL VLDL %	BLQ (derived)	BLQ (derived)	Others	Full model (covariates and genotypes)	AUROC	0.678	[0.660, 0.697]	6.3x10^-63
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Covariate-only model	AUROC	0.665	[0.655, 0.674]	1.1x10^-247
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.554	[0.544, 0.564]	8.1x10^-29
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.605	[0.596, 0.615]	6.5x10^-104
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Genotype-only model	AUROC	0.624	[0.615, 0.634]	1.4x10^-138
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.674	[0.665, 0.684]	3.2x10^-269
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.697	[0.688, 0.706]	<1.0x10^-300
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Full model (covariates and genotypes)	AUROC	0.708	[0.699, 0.717]	<1.0x10^-300
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Covariate-only model	AUROC	0.708	[0.669, 0.747]	1.4x10^-19
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.569	[0.524, 0.614]	1.3x10^-03
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.583	[0.539, 0.628]	1.4x10^-04
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Genotype-only model	AUROC	0.600	[0.557, 0.642]	1.2x10^-06
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.714	[0.674, 0.754]	2.0x10^-21
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.714	[0.675, 0.752]	8.5x10^-21
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	AUROC	0.733	[0.695, 0.772]	8.4x10^-24
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Covariate-only model	AUROC	0.649	[0.571, 0.727]	3.5x10^-04
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.556	[0.478, 0.635]	1.7x10^-01
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.620	[0.545, 0.696]	7.9x10^-03
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Genotype-only model	AUROC	0.654	[0.572, 0.736]	2.2x10^-04
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.653	[0.576, 0.729]	1.8x10^-04
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.681	[0.604, 0.759]	2.1x10^-05
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	AUROC	0.695	[0.614, 0.776]	1.2x10^-06
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Covariate-only model	AUROC	0.602	[0.555, 0.650]	5.7x10^-05
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	AUROC	0.556	[0.508, 0.605]	3.2x10^-02
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	AUROC	0.577	[0.529, 0.624]	4.5x10^-03
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Genotype-only model	AUROC	0.582	[0.533, 0.630]	1.7x10^-03
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.611	[0.564, 0.658]	9.9x10^-06
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.619	[0.573, 0.666]	1.6x10^-06
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Full model (covariates and genotypes)	AUROC	0.621	[0.574, 0.668]	8.0x10^-07
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Covariate-only model	AUROC	0.689	[0.664, 0.714]	2.2x10^-46
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.541	[0.514, 0.568]	1.9x10^-03
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.579	[0.552, 0.606]	3.2x10^-09
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Genotype-only model	AUROC	0.610	[0.583, 0.637]	2.6x10^-16
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.693	[0.668, 0.717]	1.1x10^-45
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.700	[0.676, 0.724]	6.7x10^-49
BLQ: PLs to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Full model (covariates and genotypes)	AUROC	0.712	[0.688, 0.736]	1.4x10^-54
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Covariate-only model	AUROC	0.649	[0.641, 0.657]	<1.0x10^-300
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	AUROC	0.451	[0.443, 0.459]	9.5x10^-33
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	AUROC	0.441	[0.433, 0.449]	1.8x10^-47
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Genotype-only model	AUROC	0.629	[0.622, 0.637]	1.2x10^-225
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.608	[0.600, 0.616]	1.9x10^-160
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	AUROC	0.589	[0.581, 0.597]	8.1x10^-108
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	White British	Full model (covariates and genotypes)	AUROC	0.699	[0.691, 0.706]	<1.0x10^-300
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Covariate-only model	AUROC	0.684	[0.649, 0.720]	2.7x10^-23
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.484	[0.447, 0.522]	2.2x10^-01
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	AUROC	0.458	[0.421, 0.495]	5.6x10^-03
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Genotype-only model	AUROC	0.624	[0.590, 0.658]	2.1x10^-11
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.654	[0.617, 0.690]	7.0x10^-17
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	AUROC	0.628	[0.591, 0.665]	6.4x10^-12
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	AUROC	0.725	[0.692, 0.758]	1.9x10^-31
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Covariate-only model	AUROC	0.641	[0.580, 0.701]	2.5x10^-05
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.483	[0.417, 0.549]	6.1x10^-01
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	AUROC	0.456	[0.391, 0.522]	1.7x10^-01
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Genotype-only model	AUROC	0.629	[0.566, 0.692]	4.7x10^-05
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.620	[0.560, 0.680]	2.4x10^-04
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	AUROC	0.600	[0.536, 0.664]	2.4x10^-03
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	AUROC	0.677	[0.614, 0.741]	2.1x10^-08
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Covariate-only model	AUROC	0.600	[0.554, 0.647]	4.4x10^-05
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	AUROC	0.519	[0.471, 0.566]	6.3x10^-01
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	AUROC	0.488	[0.441, 0.536]	6.4x10^-01
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Genotype-only model	AUROC	0.582	[0.535, 0.628]	2.7x10^-04
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.592	[0.546, 0.639]	7.6x10^-05
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	AUROC	0.581	[0.534, 0.628]	5.2x10^-04
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	African	Full model (covariates and genotypes)	AUROC	0.628	[0.582, 0.674]	2.0x10^-07
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Covariate-only model	AUROC	0.678	[0.657, 0.699]	6.0x10^-56
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	AUROC	0.444	[0.421, 0.467]	1.5x10^-06
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	AUROC	0.430	[0.407, 0.453]	5.7x10^-10
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Genotype-only model	AUROC	0.604	[0.582, 0.627]	3.9x10^-20
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.641	[0.619, 0.663]	4.1x10^-36
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	AUROC	0.620	[0.597, 0.642]	8.6x10^-27
BLQ: Free Chol. to Tot. Lipids in XL VLDL %	BLQ (derived)	BLQ (derived)	Others	Full model (covariates and genotypes)	AUROC	0.702	[0.681, 0.722]	3.6x10^-68
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Covariate-only model	R²	0.010	[0.008, 0.013]	3.9x10^-70
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.002	[0.001, 0.003]	6.9x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.042	[0.038, 0.046]	1.1x10^-279
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.069	[0.065, 0.074]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.006	[0.005, 0.008]	1.1x10^-43
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.050	[0.045, 0.054]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.080	[0.075, 0.085]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.007	[-0.001, 0.015]	5.2x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.011	[0.001, 0.022]	3.9x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.049	[0.028, 0.071]	4.2x10^-14
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.049	[0.028, 0.070]	6.5x10^-14
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.017	[0.004, 0.030]	9.3x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.055	[0.033, 0.077]	1.4x10^-15
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.056	[0.034, 0.078]	8.4x10^-16
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.030	[0.006, 0.054]	1.2x10^-05
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.006	[-0.005, 0.017]	4.9x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.027	[0.004, 0.050]	2.8x10^-05
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.056	[0.024, 0.088]	1.4x10^-09
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.021	[0.001, 0.042]	2.2x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.040	[0.013, 0.068]	3.2x10^-07
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.080	[0.042, 0.117]	3.6x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Covariate-only model	R²	0.050	[0.015, 0.084]	1.7x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.018	[-0.004, 0.039]	6.0x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.012	[-0.006, 0.031]	1.2x10^-01
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.072	[0.031, 0.113]	1.3x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.001	[-0.003, 0.004]	7.4x10^-01
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.031	[0.003, 0.059]	1.3x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.111	[0.063, 0.159]	1.7x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Covariate-only model	R²	0.022	[0.013, 0.031]	2.6x10^-17
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.003	[-0.000, 0.007]	8.1x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.037	[0.026, 0.049]	1.3x10^-28
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.062	[0.048, 0.075]	1.7x10^-46
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.016	[0.008, 0.023]	7.6x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.052	[0.039, 0.065]	2.9x10^-39
PLs to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.078	[0.063, 0.093]	7.3x10^-59
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Covariate-only model	R²	0.016	[0.014, 0.019]	1.7x10^-111
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.004	[0.003, 0.006]	7.3x10^-31
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.030	[0.027, 0.033]	7.3x10^-208
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.030	[0.027, 0.033]	7.8x10^-208
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.008	[0.007, 0.010]	1.1x10^-59
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.047	[0.043, 0.051]	<1.0x10^-300
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.047	[0.043, 0.051]	<1.0x10^-300
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.016	[0.003, 0.028]	1.4x10^-05
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.005	[-0.002, 0.012]	1.6x10^-02
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.037	[0.018, 0.055]	2.5x10^-11
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.027	[0.011, 0.043]	1.2x10^-08
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.008	[-0.001, 0.016]	2.4x10^-03
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.052	[0.031, 0.074]	1.1x10^-15
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.043	[0.023, 0.063]	4.8x10^-13
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.012	[-0.003, 0.028]	4.6x10^-03
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.005	[-0.005, 0.014]	8.3x10^-02
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.012	[-0.003, 0.028]	4.1x10^-03
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.013	[-0.003, 0.029]	3.7x10^-03
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.007	[-0.005, 0.018]	3.6x10^-02
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.026	[0.003, 0.048]	3.7x10^-05
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.026	[0.003, 0.048]	3.7x10^-05
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Covariate-only model	R²	0.003	[-0.006, 0.012]	3.7x10^-01
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.000	[-0.002, 0.002]	8.5x10^-01
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.007	[-0.007, 0.021]	1.8x10^-01
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.010	[-0.006, 0.026]	1.1x10^-01
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.003	[-0.006, 0.013]	3.5x10^-01
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.011	[-0.006, 0.027]	9.8x10^-02
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.012	[-0.006, 0.029]	8.2x10^-02
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Covariate-only model	R²	0.038	[0.027, 0.049]	3.1x10^-30
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.003	[-0.000, 0.007]	6.7x10^-04
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.030	[0.020, 0.040]	2.8x10^-24
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.032	[0.022, 0.042]	1.1x10^-25
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.031	[0.021, 0.041]	9.6x10^-25
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.067	[0.052, 0.081]	2.7x10^-52
CE to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.066	[0.052, 0.080]	9.6x10^-52
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Covariate-only model	R²	0.044	[0.040, 0.048]	8.0x10^-286
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.007	[0.005, 0.008]	2.8x10^-44
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.041	[0.037, 0.044]	1.3x10^-264
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.045	[0.041, 0.049]	4.7x10^-296
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.011	[0.009, 0.013]	1.9x10^-69
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.082	[0.077, 0.087]	<1.0x10^-300
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.091	[0.086, 0.096]	<1.0x10^-300
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.034	[0.016, 0.052]	5.8x10^-10
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.000	[-0.002, 0.002]	5.0x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.016	[0.003, 0.028]	2.9x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.018	[0.005, 0.031]	8.6x10^-06
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.016	[0.004, 0.029]	2.2x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.044	[0.024, 0.063]	2.7x10^-12
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.053	[0.031, 0.074]	1.3x10^-14
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.028	[0.005, 0.052]	2.7x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.003	[-0.005, 0.010]	1.9x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.028	[0.005, 0.052]	2.7x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.044	[0.015, 0.072]	1.6x10^-07
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.009	[-0.004, 0.023]	1.6x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.057	[0.025, 0.089]	1.9x10^-09
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.067	[0.032, 0.101]	7.0x10^-11
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Covariate-only model	R²	0.025	[0.000, 0.051]	3.3x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.011	[-0.006, 0.028]	1.6x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.075	[0.034, 0.117]	1.9x10^-04
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.085	[0.042, 0.129]	6.7x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.006	[-0.007, 0.019]	2.8x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.100	[0.054, 0.147]	1.5x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.087	[0.043, 0.131]	5.9x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Covariate-only model	R²	0.054	[0.041, 0.067]	1.4x10^-39
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.003	[-0.000, 0.006]	3.9x10^-03
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.036	[0.025, 0.047]	8.9x10^-27
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.042	[0.031, 0.054]	2.3x10^-31
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.022	[0.014, 0.031]	3.8x10^-17
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.086	[0.070, 0.102]	1.5x10^-63
Free Chol. to Tot. Lipids in CMs and XXL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.097	[0.080, 0.114]	2.6x10^-71
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Covariate-only model	R²	0.011	[0.008, 0.013]	5.1x10^-81
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.007	[0.005, 0.008]	3.1x10^-52
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.039	[0.035, 0.042]	4.2x10^-297
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.056	[0.052, 0.061]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.012	[0.010, 0.014]	6.5x10^-92
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.047	[0.043, 0.052]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.067	[0.062, 0.072]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.022	[0.008, 0.037]	4.3x10^-08
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.011	[0.001, 0.021]	1.3x10^-04
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.044	[0.024, 0.064]	9.6x10^-15
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.057	[0.035, 0.080]	6.1x10^-19
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.020	[0.006, 0.034]	1.8x10^-07
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.058	[0.035, 0.080]	4.8x10^-19
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.077	[0.051, 0.102]	5.6x10^-25
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.009	[-0.004, 0.023]	1.3x10^-02
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.002	[-0.005, 0.009]	2.2x10^-01
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.013	[-0.003, 0.030]	2.4x10^-03
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.038	[0.011, 0.065]	2.4x10^-07
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.006	[-0.005, 0.016]	5.1x10^-02
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.019	[-0.000, 0.038]	3.2x10^-04
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.047	[0.018, 0.077]	8.5x10^-09
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Covariate-only model	R²	0.009	[-0.006, 0.024]	8.3x10^-02
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.005	[-0.006, 0.016]	2.1x10^-01
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.015	[-0.005, 0.035]	2.3x10^-02
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.048	[0.014, 0.082]	4.7x10^-05
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.001	[-0.004, 0.006]	5.7x10^-01
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.022	[-0.002, 0.046]	6.6x10^-03
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.056	[0.020, 0.093]	1.1x10^-05
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Covariate-only model	R²	0.009	[0.004, 0.015]	3.5x10^-09
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.003	[-0.000, 0.006]	6.1x10^-04
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.029	[0.019, 0.039]	3.7x10^-26
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.051	[0.038, 0.064]	1.1x10^-44
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.008	[0.002, 0.013]	1.0x10^-07
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.037	[0.026, 0.049]	4.9x10^-33
PLs to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.061	[0.047, 0.075]	1.7x10^-53
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Covariate-only model	R²	0.059	[0.055, 0.064]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.006	[0.005, 0.008]	5.7x10^-45
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.067	[0.062, 0.072]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.073	[0.068, 0.078]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.006	[0.004, 0.007]	2.5x10^-43
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.127	[0.121, 0.133]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.134	[0.128, 0.140]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.061	[0.038, 0.085]	9.5x10^-19
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.003	[-0.002, 0.008]	6.0x10^-02
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.058	[0.035, 0.081]	8.8x10^-18
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.063	[0.039, 0.086]	3.4x10^-19
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.009	[-0.000, 0.018]	8.9x10^-04
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.118	[0.088, 0.149]	9.9x10^-36
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.123	[0.093, 0.154]	3.2x10^-37
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.013	[-0.003, 0.029]	3.6x10^-03
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.011	[-0.004, 0.025]	8.2x10^-03
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.046	[0.017, 0.075]	3.3x10^-08
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.045	[0.016, 0.074]	4.2x10^-08
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.000	[-0.002, 0.003]	6.3x10^-01
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.061	[0.028, 0.095]	1.4x10^-10
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.055	[0.024, 0.087]	1.1x10^-09
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Covariate-only model	R²	0.006	[-0.007, 0.018]	2.1x10^-01
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.010	[-0.006, 0.026]	1.0x10^-01
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.059	[0.021, 0.096]	6.8x10^-05
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.062	[0.024, 0.101]	3.9x10^-05
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.001	[-0.004, 0.006]	6.2x10^-01
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.062	[0.024, 0.100]	4.2x10^-05
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.053	[0.017, 0.088]	1.7x10^-04
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Covariate-only model	R²	0.049	[0.036, 0.061]	6.8x10^-40
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.006	[0.001, 0.011]	5.0x10^-06
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.077	[0.061, 0.092]	2.3x10^-62
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.085	[0.069, 0.101]	3.6x10^-69
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.005	[0.001, 0.010]	1.8x10^-05
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.123	[0.105, 0.141]	1.5x10^-101
Free Chol. to Tot. Lipids in XL VLDL % (BLQ removed)	Derived (percentage traits, excl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.131	[0.113, 0.150]	9.6x10^-109
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Covariate-only model	R²	0.025	[0.022, 0.029]	7.5x10^-208
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.017	[0.015, 0.020]	2.7x10^-143
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.027	[0.024, 0.030]	3.4x10^-219
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.017	[0.014, 0.019]	1.3x10^-137
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.041	[0.038, 0.045]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.042	[0.038, 0.046]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.049	[0.045, 0.053]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.026	[0.023, 0.029]	1.8x10^-212
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.066	[0.062, 0.071]	<1.0x10^-300
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.034	[0.016, 0.052]	9.8x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.016	[0.003, 0.028]	1.7x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.014	[0.002, 0.026]	4.5x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.022	[0.008, 0.037]	8.7x10^-09
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.037	[0.018, 0.055]	1.3x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.050	[0.029, 0.072]	3.4x10^-18
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.049	[0.028, 0.070]	1.3x10^-17
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.035	[0.017, 0.052]	7.0x10^-13
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.070	[0.046, 0.095]	5.5x10^-25
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.009	[-0.004, 0.023]	8.9x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.011	[-0.004, 0.025]	5.3x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.022	[0.001, 0.043]	5.5x10^-05
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.009	[-0.005, 0.022]	1.1x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.024	[0.002, 0.045]	2.9x10^-05
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.019	[-0.000, 0.039]	1.5x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.027	[0.004, 0.049]	9.3x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.010	[-0.004, 0.025]	5.7x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.031	[0.007, 0.056]	1.5x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Covariate-only model	R²	0.031	[0.003, 0.060]	1.2x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.011	[-0.006, 0.028]	2.4x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.017	[-0.004, 0.038]	4.5x10^-03
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.011	[-0.006, 0.027]	2.5x10^-02
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.029	[0.002, 0.056]	2.2x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.040	[0.009, 0.072]	1.3x10^-05
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.046	[0.013, 0.079]	3.0x10^-06
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.031	[0.003, 0.060]	1.2x10^-04
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.056	[0.020, 0.093]	2.2x10^-07
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Covariate-only model	R²	0.034	[0.024, 0.045]	3.3x10^-33
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.023	[0.014, 0.032]	1.3x10^-22
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.021	[0.012, 0.029]	1.0x10^-20
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.026	[0.017, 0.035]	2.7x10^-25
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.038	[0.027, 0.049]	1.5x10^-36
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.053	[0.040, 0.066]	9.5x10^-51
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.054	[0.041, 0.067]	1.7x10^-51
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.034	[0.023, 0.044]	1.7x10^-32
PLs to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.071	[0.056, 0.085]	1.9x10^-67
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Covariate-only model	R²	0.010	[0.008, 0.011]	9.1x10^-79
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.003	[0.002, 0.004]	7.3x10^-26
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.029	[0.026, 0.033]	1.1x10^-241
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.009	[0.007, 0.010]	4.7x10^-71
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.031	[0.028, 0.034]	1.9x10^-254
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.004	[0.003, 0.006]	3.0x10^-37
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.039	[0.035, 0.043]	1.7x10^-308
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.010	[0.008, 0.012]	1.8x10^-79
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.041	[0.037, 0.045]	<1.0x10^-300
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.004	[-0.002, 0.011]	1.2x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.001	[-0.002, 0.005]	1.7x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.026	[0.010, 0.042]	4.9x10^-10
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.001	[-0.002, 0.005]	1.6x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.030	[0.013, 0.047]	2.1x10^-11
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.002	[-0.002, 0.007]	8.4x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.028	[0.012, 0.045]	8.0x10^-11
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.004	[-0.002, 0.011]	1.2x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.032	[0.015, 0.050]	3.5x10^-12
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.006	[-0.005, 0.017]	3.6x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.003	[-0.005, 0.010]	1.7x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.015	[-0.002, 0.032]	9.5x10^-04
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.007	[-0.005, 0.019]	2.5x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.013	[-0.003, 0.028]	2.4x10^-03
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.003	[-0.005, 0.011]	1.2x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.020	[0.000, 0.040]	1.1x10^-04
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.007	[-0.005, 0.018]	2.9x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.018	[-0.001, 0.037]	2.7x10^-04
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Covariate-only model	R²	0.013	[-0.005, 0.032]	1.2x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.002	[-0.005, 0.008]	3.8x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.013	[-0.005, 0.032]	1.3x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.002	[-0.005, 0.008]	3.9x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.011	[-0.006, 0.029]	2.1x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.010	[-0.006, 0.026]	3.0x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.000	[-0.001, 0.002]	8.5x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.014	[-0.005, 0.033]	1.0x10^-02
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.000	[-0.000, 0.000]	9.8x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Covariate-only model	R²	0.020	[0.012, 0.028]	1.4x10^-19
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.000	[-0.001, 0.002]	1.6x10^-01
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.026	[0.017, 0.036]	1.5x10^-25
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.003	[-0.000, 0.007]	2.5x10^-04
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.026	[0.016, 0.035]	5.4x10^-25
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.015	[0.008, 0.023]	1.1x10^-15
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.040	[0.029, 0.052]	1.0x10^-38
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.018	[0.010, 0.026]	7.1x10^-18
CE to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.042	[0.030, 0.053]	5.0x10^-40
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Covariate-only model	R²	0.022	[0.019, 0.025]	9.8x10^-180
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.012	[0.009, 0.014]	1.4x10^-95
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.033	[0.030, 0.037]	6.7x10^-272
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.018	[0.015, 0.020]	1.3x10^-145
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.036	[0.032, 0.039]	8.5x10^-294
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.005	[0.004, 0.006]	9.7x10^-42
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.049	[0.045, 0.054]	<1.0x10^-300
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.022	[0.019, 0.025]	7.7x10^-182
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.058	[0.054, 0.063]	<1.0x10^-300
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.028	[0.012, 0.045]	9.0x10^-11
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.004	[-0.002, 0.011]	1.4x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.017	[0.004, 0.030]	4.2x10^-07
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.008	[-0.001, 0.017]	5.2x10^-04
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.025	[0.010, 0.041]	9.0x10^-10
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.013	[0.002, 0.024]	1.1x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.045	[0.025, 0.065]	2.5x10^-16
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.029	[0.012, 0.045]	6.8x10^-11
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.053	[0.031, 0.075]	3.4x10^-19
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.012	[-0.003, 0.028]	2.4x10^-03
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.008	[-0.005, 0.021]	1.3x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.022	[0.001, 0.043]	4.9x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.009	[-0.005, 0.022]	1.2x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.015	[-0.002, 0.032]	8.9x10^-04
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.003	[-0.005, 0.011]	1.4x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.026	[0.003, 0.048]	1.3x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.012	[-0.003, 0.028]	2.9x10^-03
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.026	[0.003, 0.048]	1.2x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Covariate-only model	R²	0.008	[-0.006, 0.023]	5.1x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.000	[-0.000, 0.000]	9.8x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.019	[-0.003, 0.042]	2.6x10^-03
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.000	[-0.001, 0.001]	8.8x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.023	[-0.001, 0.047]	9.7x10^-04
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.007	[-0.007, 0.021]	6.3x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.001	[-0.004, 0.006]	5.0x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.009	[-0.006, 0.024]	4.2x10^-02
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.000	[-0.003, 0.004]	6.3x10^-01
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Covariate-only model	R²	0.024	[0.015, 0.033]	1.0x10^-23
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.002	[-0.001, 0.004]	6.5x10^-03
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.019	[0.011, 0.027]	1.1x10^-18
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.004	[0.001, 0.008]	1.7x10^-05
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.020	[0.012, 0.028]	9.8x10^-20
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.014	[0.007, 0.021]	2.1x10^-14
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.040	[0.029, 0.052]	1.5x10^-38
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.024	[0.015, 0.033]	2.7x10^-23
Free Chol. to Tot. Lipids in CMs and XXL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.044	[0.032, 0.056]	2.2x10^-42
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Covariate-only model	R²	0.021	[0.018, 0.024]	2.3x10^-175
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.019	[0.016, 0.022]	1.0x10^-159
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.030	[0.027, 0.034]	4.4x10^-256
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.023	[0.020, 0.026]	6.7x10^-197
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.037	[0.033, 0.041]	1.7x10^-308
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.040	[0.036, 0.044]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.047	[0.043, 0.052]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.022	[0.019, 0.025]	3.6x10^-183
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.058	[0.054, 0.063]	<1.0x10^-300
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.043	[0.023, 0.062]	4.1x10^-16
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.012	[0.001, 0.023]	1.5x10^-05
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.028	[0.012, 0.045]	4.2x10^-11
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.019	[0.006, 0.033]	5.7x10^-08
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.023	[0.009, 0.038]	1.9x10^-09
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.050	[0.029, 0.071]	9.1x10^-19
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.069	[0.044, 0.093]	2.4x10^-25
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.044	[0.024, 0.064]	1.6x10^-16
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.062	[0.039, 0.085]	6.1x10^-23
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.010	[-0.004, 0.024]	7.4x10^-03
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.014	[-0.003, 0.030]	1.4x10^-03
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.027	[0.004, 0.050]	7.6x10^-06
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.012	[-0.004, 0.027]	3.5x10^-03
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.021	[0.000, 0.041]	9.1x10^-05
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.022	[0.001, 0.043]	5.0x10^-05
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.026	[0.003, 0.048]	1.3x10^-05
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.010	[-0.004, 0.024]	7.6x10^-03
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.027	[0.004, 0.050]	7.6x10^-06
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Covariate-only model	R²	0.010	[-0.006, 0.026]	2.1x10^-02
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.003	[-0.006, 0.013]	1.7x10^-01
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.018	[-0.003, 0.040]	1.5x10^-03
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.009	[-0.006, 0.024]	2.8x10^-02
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.021	[-0.002, 0.044]	7.1x10^-04
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.012	[-0.006, 0.030]	1.0x10^-02
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.021	[-0.002, 0.044]	7.1x10^-04
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.010	[-0.006, 0.026]	2.2x10^-02
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.028	[0.001, 0.054]	9.3x10^-05
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Covariate-only model	R²	0.035	[0.024, 0.046]	8.5x10^-35
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.013	[0.006, 0.019]	2.3x10^-13
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.020	[0.011, 0.028]	5.5x10^-20
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.011	[0.005, 0.017]	8.9x10^-12
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.023	[0.014, 0.032]	1.3x10^-23
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.042	[0.031, 0.054]	6.2x10^-42
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.052	[0.039, 0.065]	2.4x10^-51
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.035	[0.024, 0.046]	1.1x10^-34
PLs to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.055	[0.042, 0.069]	1.2x10^-54
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Covariate-only model	R²	0.050	[0.046, 0.054]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Genotype-only model	R²	0.009	[0.007, 0.011]	5.2x10^-78
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Genotype-only model	R²	0.059	[0.055, 0.064]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.016	[0.014, 0.019]	1.6x10^-138
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.058	[0.053, 0.063]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	White British	Full model (covariates and genotypes)	R²	0.005	[0.004, 0.007]	2.9x10^-47
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.108	[0.102, 0.114]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.049	[0.045, 0.053]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.109	[0.103, 0.114]	<1.0x10^-300
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.056	[0.034, 0.079]	5.7x10^-21
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Genotype-only model	R²	0.005	[-0.002, 0.012]	6.4x10^-03
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.059	[0.036, 0.082]	5.7x10^-22
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.018	[0.005, 0.032]	1.1x10^-07
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.054	[0.032, 0.076]	3.4x10^-20
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	non-British White	Full model (covariates and genotypes)	R²	0.010	[0.000, 0.020]	9.9x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.115	[0.085, 0.144]	4.5x10^-42
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.056	[0.034, 0.078]	9.1x10^-21
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.111	[0.082, 0.141]	8.4x10^-41
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.014	[-0.003, 0.031]	1.2x10^-03
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Genotype-only model	R²	0.008	[-0.005, 0.020]	1.9x10^-02
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.054	[0.022, 0.085]	1.7x10^-10
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.022	[0.001, 0.043]	5.4x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.049	[0.019, 0.079]	1.2x10^-09
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	South Asian	Full model (covariates and genotypes)	R²	0.000	[-0.002, 0.003]	6.7x10^-01
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.058	[0.025, 0.090]	3.8x10^-11
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.014	[-0.003, 0.031]	1.1x10^-03
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.061	[0.028, 0.094]	1.1x10^-11
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Covariate-only model	R²	0.010	[-0.006, 0.026]	2.0x10^-02
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Genotype-only model	R²	0.006	[-0.007, 0.018]	7.7x10^-02
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Genotype-only model	R²	0.032	[0.004, 0.060]	2.7x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.006	[-0.007, 0.018]	7.9x10^-02
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.027	[0.001, 0.053]	1.2x10^-04
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	African	Full model (covariates and genotypes)	R²	0.000	[-0.002, 0.003]	7.1x10^-01
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.035	[0.005, 0.064]	1.2x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.009	[-0.006, 0.025]	2.4x10^-02
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.035	[0.006, 0.065]	1.0x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Covariate-only model	R²	0.044	[0.032, 0.056]	9.0x10^-44
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Genotype-only model	R²	0.010	[0.004, 0.016]	4.5x10^-11
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Genotype-only model	R²	0.065	[0.051, 0.079]	3.1x10^-64
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.016	[0.009, 0.024]	4.4x10^-17
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.066	[0.052, 0.080]	3.6x10^-65
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	BLQ (derived)	Others	Full model (covariates and genotypes)	R²	0.004	[0.000, 0.008]	1.5x10^-05
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.102	[0.085, 0.119]	4.9x10^-101
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.041	[0.030, 0.053]	6.5x10^-41
Free Chol. to Tot. Lipids in XL VLDL %	Derived (percentage traits, incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.105	[0.088, 0.122]	2.0x10^-104
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Covariate-only model	R²	0.063	[0.058, 0.067]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.083	[0.077, 0.088]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.085	[0.080, 0.090]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.030	[0.027, 0.033]	3.3x10^-256
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.102	[0.096, 0.108]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.085	[0.079, 0.090]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.148	[0.141, 0.154]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.031	[0.028, 0.034]	1.6x10^-263
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.166	[0.159, 0.173]	<1.0x10^-300
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.064	[0.040, 0.088]	7.8x10^-24
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.078	[0.052, 0.103]	9.7x10^-29
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.091	[0.063, 0.118]	1.7x10^-33
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.024	[0.009, 0.039]	9.0x10^-10
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.105	[0.076, 0.134]	5.9x10^-39
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.080	[0.054, 0.106]	1.4x10^-29
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.156	[0.122, 0.189]	3.1x10^-58
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.025	[0.010, 0.041]	4.3x10^-10
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.171	[0.137, 0.206]	1.4x10^-64
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.020	[0.000, 0.040]	1.2x10^-04
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.065	[0.031, 0.099]	1.8x10^-12
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.088	[0.049, 0.126]	1.7x10^-16
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.030	[0.006, 0.054]	2.3x10^-06
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.102	[0.061, 0.143]	5.2x10^-19
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.066	[0.032, 0.101]	1.1x10^-12
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.086	[0.047, 0.124]	4.5x10^-16
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.030	[0.006, 0.054]	2.4x10^-06
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.110	[0.067, 0.152]	2.1x10^-20
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Covariate-only model	R²	0.027	[0.001, 0.053]	8.9x10^-05
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.030	[0.003, 0.058]	3.2x10^-05
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.016	[-0.005, 0.036]	2.9x10^-03
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.017	[-0.004, 0.038]	1.7x10^-03
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.029	[0.002, 0.057]	4.0x10^-05
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.031	[0.003, 0.059]	2.5x10^-05
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.041	[0.009, 0.073]	1.2x10^-06
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.018	[-0.004, 0.039]	1.5x10^-03
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.056	[0.019, 0.092]	1.3x10^-08
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Covariate-only model	R²	0.091	[0.074, 0.107]	1.4x10^-90
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.068	[0.053, 0.082]	2.3x10^-67
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.063	[0.049, 0.077]	5.0x10^-63
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.018	[0.010, 0.026]	4.3x10^-19
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.081	[0.065, 0.096]	2.1x10^-80
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.071	[0.056, 0.085]	2.4x10^-70
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.150	[0.130, 0.169]	2.8x10^-153
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.019	[0.011, 0.028]	4.3x10^-20
PLs in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.166	[0.146, 0.187]	1.0x10^-171
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Covariate-only model	R²	0.062	[0.058, 0.067]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.083	[0.078, 0.089]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.093	[0.088, 0.099]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.012	[0.010, 0.014]	5.8x10^-105
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.109	[0.104, 0.115]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.085	[0.080, 0.091]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.156	[0.149, 0.163]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.013	[0.010, 0.015]	3.7x10^-107
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.173	[0.166, 0.180]	<1.0x10^-300
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.067	[0.043, 0.091]	9.2x10^-25
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.089	[0.062, 0.116]	7.3x10^-33
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.104	[0.075, 0.132]	2.6x10^-38
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.017	[0.004, 0.030]	2.5x10^-07
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.110	[0.080, 0.139]	1.0x10^-40
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.091	[0.064, 0.119]	1.1x10^-33
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.169	[0.135, 0.203]	1.4x10^-63
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.018	[0.005, 0.031]	1.9x10^-07
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.178	[0.143, 0.212]	4.5x10^-67
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.021	[0.000, 0.041]	8.7x10^-05
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.065	[0.031, 0.099]	1.6x10^-12
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.100	[0.059, 0.141]	9.5x10^-19
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.001	[-0.004, 0.006]	3.3x10^-01
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.105	[0.064, 0.147]	1.1x10^-19
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.066	[0.031, 0.100]	1.4x10^-12
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.095	[0.055, 0.135]	8.8x10^-18
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.002	[-0.004, 0.007]	2.9x10^-01
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.112	[0.070, 0.155]	6.7x10^-21
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Covariate-only model	R²	0.033	[0.004, 0.061]	1.4x10^-05
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.020	[-0.003, 0.043]	7.1x10^-04
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.029	[0.002, 0.057]	3.8x10^-05
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.001	[-0.004, 0.007]	4.2x10^-01
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.041	[0.009, 0.072]	1.2x10^-06
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.021	[-0.002, 0.044]	5.8x10^-04
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.060	[0.022, 0.097]	3.9x10^-09
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.001	[-0.005, 0.007]	4.0x10^-01
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.073	[0.032, 0.114]	6.4x10^-11
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Covariate-only model	R²	0.092	[0.076, 0.108]	4.2x10^-92
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.061	[0.047, 0.075]	1.2x10^-60
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.066	[0.052, 0.081]	4.3x10^-66
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.013	[0.006, 0.019]	1.1x10^-13
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.082	[0.066, 0.097]	1.5x10^-81
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.063	[0.049, 0.077]	4.2x10^-63
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.152	[0.133, 0.172]	2.8x10^-156
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.013	[0.006, 0.020]	4.5x10^-14
CE in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.166	[0.146, 0.186]	1.8x10^-171
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Covariate-only model	R²	0.059	[0.054, 0.063]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.084	[0.079, 0.090]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.084	[0.079, 0.090]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.023	[0.020, 0.025]	6.1x10^-192
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.104	[0.098, 0.110]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.086	[0.081, 0.091]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.142	[0.135, 0.148]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.023	[0.020, 0.026]	1.5x10^-195
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.164	[0.157, 0.171]	<1.0x10^-300
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.059	[0.037, 0.082]	3.5x10^-22
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.085	[0.059, 0.112]	1.5x10^-31
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.091	[0.064, 0.119]	8.4x10^-34
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.027	[0.011, 0.043]	1.2x10^-10
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.107	[0.078, 0.137]	9.5x10^-40
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.087	[0.060, 0.114]	4.4x10^-32
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.149	[0.117, 0.182]	8.1x10^-56
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.027	[0.011, 0.043]	7.9x10^-11
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.169	[0.135, 0.203]	1.3x10^-63
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.017	[-0.001, 0.036]	3.1x10^-04
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.070	[0.035, 0.106]	2.1x10^-13
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.083	[0.045, 0.121]	1.2x10^-15
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.012	[-0.004, 0.027]	3.3x10^-03
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.100	[0.059, 0.141]	9.6x10^-19
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.071	[0.035, 0.106]	1.7x10^-13
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.076	[0.039, 0.112]	2.2x10^-14
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.012	[-0.003, 0.028]	2.3x10^-03
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.105	[0.064, 0.147]	1.3x10^-19
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Covariate-only model	R²	0.028	[0.001, 0.054]	6.9x10^-05
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.023	[-0.001, 0.047]	3.3x10^-04
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.017	[-0.004, 0.038]	1.8x10^-03
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.001	[-0.004, 0.006]	4.9x10^-01
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.032	[0.003, 0.060]	2.0x10^-05
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.023	[-0.001, 0.047]	3.0x10^-04
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.043	[0.011, 0.075]	6.3x10^-07
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.001	[-0.004, 0.006]	4.7x10^-01
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.059	[0.022, 0.096]	4.8x10^-09
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Covariate-only model	R²	0.088	[0.072, 0.104]	5.1x10^-88
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.065	[0.051, 0.080]	4.1x10^-65
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.061	[0.048, 0.075]	3.3x10^-61
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.021	[0.012, 0.029]	1.4x10^-21
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.080	[0.064, 0.095]	1.5x10^-79
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.067	[0.053, 0.082]	5.9x10^-67
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.144	[0.124, 0.163]	5.0x10^-147
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.022	[0.013, 0.030]	3.4x10^-22
Free Chol. in CMs and XXL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.163	[0.143, 0.183]	2.8x10^-168
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Covariate-only model	R²	0.067	[0.062, 0.072]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.062	[0.057, 0.067]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.094	[0.089, 0.100]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.034	[0.030, 0.037]	3.4x10^-289
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.106	[0.100, 0.111]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.064	[0.059, 0.068]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.162	[0.156, 0.169]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.035	[0.032, 0.039]	3.7x10^-301
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.174	[0.167, 0.181]	<1.0x10^-300
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.074	[0.049, 0.099]	2.0x10^-27
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.057	[0.035, 0.079]	2.5x10^-21
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.098	[0.070, 0.126]	3.7x10^-36
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.035	[0.017, 0.053]	1.9x10^-13
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.101	[0.073, 0.130]	1.8x10^-37
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.059	[0.036, 0.082]	5.0x10^-22
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.173	[0.139, 0.208]	2.2x10^-65
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.036	[0.018, 0.055]	5.1x10^-14
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.177	[0.143, 0.212]	4.8x10^-67
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.029	[0.005, 0.053]	2.9x10^-06
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.042	[0.014, 0.071]	1.5x10^-08
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.089	[0.050, 0.128]	9.4x10^-17
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.030	[0.006, 0.055]	1.7x10^-06
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.094	[0.055, 0.134]	1.1x10^-17
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.043	[0.015, 0.072]	1.1x10^-08
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.102	[0.061, 0.144]	4.2x10^-19
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.030	[0.006, 0.054]	2.0x10^-06
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.115	[0.072, 0.158]	2.5x10^-21
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Covariate-only model	R²	0.040	[0.008, 0.071]	1.8x10^-06
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.023	[-0.001, 0.047]	3.0x10^-04
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.029	[0.002, 0.055]	5.0x10^-05
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.017	[-0.004, 0.038]	1.7x10^-03
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.044	[0.011, 0.077]	4.6x10^-07
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.024	[-0.001, 0.048]	2.4x10^-04
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.064	[0.025, 0.103]	9.4x10^-10
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.018	[-0.003, 0.040]	1.3x10^-03
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.081	[0.038, 0.123]	5.4x10^-12
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Covariate-only model	R²	0.100	[0.083, 0.117]	1.1x10^-100
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.054	[0.041, 0.067]	1.1x10^-53
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.076	[0.060, 0.091]	2.0x10^-75
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.019	[0.011, 0.028]	4.3x10^-20
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.084	[0.068, 0.100]	6.2x10^-84
PLs in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.056	[0.043, 0.070]	6.5x10^-56
PLs in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.164	[0.144, 0.184]	6.3x10^-169
PLs in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.021	[0.012, 0.029]	1.5x10^-21
PLs in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.173	[0.152, 0.193]	3.8x10^-179
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Covariate-only model	R²	0.063	[0.059, 0.068]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.075	[0.070, 0.080]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.090	[0.085, 0.095]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Genotype-only model	R²	0.018	[0.016, 0.021]	2.1x10^-156
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.106	[0.100, 0.112]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.076	[0.071, 0.082]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.153	[0.147, 0.160]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.018	[0.015, 0.020]	2.9x10^-151
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.171	[0.164, 0.178]	<1.0x10^-300
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Covariate-only model	R²	0.071	[0.046, 0.096]	2.4x10^-26
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.066	[0.042, 0.090]	1.8x10^-24
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.099	[0.071, 0.128]	9.0x10^-37
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.014	[0.002, 0.025]	4.3x10^-06
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.103	[0.075, 0.132]	3.1x10^-38
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.067	[0.043, 0.091]	6.9x10^-25
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.171	[0.137, 0.205]	2.2x10^-64
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.013	[0.002, 0.025]	6.2x10^-06
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.176	[0.142, 0.211]	1.5x10^-66
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Covariate-only model	R²	0.028	[0.005, 0.052]	4.4x10^-06
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.073	[0.037, 0.109]	6.2x10^-14
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.085	[0.047, 0.123]	4.8x10^-16
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.012	[-0.003, 0.028]	2.4x10^-03
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.093	[0.053, 0.133]	1.9x10^-17
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.073	[0.037, 0.109]	7.7x10^-14
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.093	[0.054, 0.133]	1.8x10^-17
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.013	[-0.003, 0.029]	2.0x10^-03
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.112	[0.069, 0.154]	9.3x10^-21
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Covariate-only model	R²	0.039	[0.008, 0.069]	2.5x10^-06
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.033	[0.004, 0.062]	1.3x10^-05
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.019	[-0.003, 0.041]	1.0x10^-03
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Genotype-only model	R²	0.004	[-0.006, 0.015]	1.3x10^-01
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.046	[0.012, 0.079]	2.8x10^-07
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.033	[0.004, 0.062]	1.3x10^-05
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.056	[0.019, 0.092]	1.3x10^-08
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.004	[-0.006, 0.013]	1.5x10^-01
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.081	[0.038, 0.124]	4.8x10^-12
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Covariate-only model	R²	0.098	[0.081, 0.115]	2.4x10^-98
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.061	[0.048, 0.075]	3.1x10^-61
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.066	[0.052, 0.080]	7.5x10^-66
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Genotype-only model	R²	0.025	[0.016, 0.034]	1.7x10^-25
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.083	[0.068, 0.099]	2.0x10^-83
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.063	[0.049, 0.077]	1.4x10^-62
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.154	[0.134, 0.174]	2.8x10^-158
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Derived (percentage traits, incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.024	[0.015, 0.033]	1.6x10^-24
Free Chol. in XL VLDL	Original (incl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.169	[0.149, 0.190]	2.9x10^-175
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Covariate-only model	R²	0.034	[0.030, 0.037]	3.4x10^-223
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.055	[0.050, 0.059]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.072	[0.067, 0.077]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.062	[0.058, 0.067]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.056	[0.051, 0.060]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.111	[0.105, 0.117]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.101	[0.095, 0.107]	<1.0x10^-300
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.023	[0.008, 0.038]	3.0x10^-07
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.049	[0.028, 0.071]	4.1x10^-14
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.080	[0.054, 0.106]	2.7x10^-22
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.073	[0.048, 0.098]	2.4x10^-20
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.050	[0.029, 0.072]	2.5x10^-14
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.109	[0.080, 0.139]	3.5x10^-30
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.100	[0.071, 0.128]	1.5x10^-27
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.011	[-0.004, 0.026]	7.5x10^-03
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.042	[0.014, 0.071]	1.5x10^-07
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.076	[0.040, 0.113]	1.1x10^-12
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.066	[0.032, 0.101]	3.7x10^-11
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.043	[0.015, 0.072]	1.2x10^-07
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.086	[0.048, 0.124]	3.9x10^-14
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.070	[0.035, 0.105]	1.1x10^-11
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Covariate-only model	R²	0.002	[-0.005, 0.009]	5.5x10^-01
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.013	[-0.006, 0.031]	1.2x10^-01
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.019	[-0.003, 0.041]	5.2x10^-02
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.007	[-0.007, 0.020]	2.5x10^-01
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.012	[-0.006, 0.030]	1.2x10^-01
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.017	[-0.004, 0.038]	6.9x10^-02
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.007	[-0.007, 0.021]	2.4x10^-01
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Covariate-only model	R²	0.045	[0.032, 0.057]	8.1x10^-34
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.046	[0.034, 0.058]	1.1x10^-34
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.062	[0.048, 0.076]	8.6x10^-47
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.053	[0.040, 0.066]	2.7x10^-40
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.047	[0.035, 0.059]	1.3x10^-35
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.111	[0.093, 0.129]	1.2x10^-84
Trunc.: PLs in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.103	[0.086, 0.120]	2.2x10^-78
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Covariate-only model	R²	0.035	[0.032, 0.039]	2.6x10^-246
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.058	[0.054, 0.063]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.082	[0.077, 0.087]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.073	[0.068, 0.078]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.059	[0.055, 0.064]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.122	[0.116, 0.128]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.114	[0.108, 0.120]	<1.0x10^-300
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.027	[0.011, 0.043]	1.1x10^-08
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.069	[0.045, 0.094]	2.0x10^-20
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.087	[0.060, 0.114]	2.1x10^-25
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.083	[0.057, 0.110]	1.7x10^-24
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.070	[0.046, 0.095]	9.8x10^-21
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.119	[0.089, 0.150]	7.5x10^-35
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.114	[0.085, 0.144]	1.8x10^-33
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.020	[-0.000, 0.039]	3.1x10^-04
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.047	[0.017, 0.076]	2.0x10^-08
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.089	[0.050, 0.127]	5.4x10^-15
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.082	[0.044, 0.119]	6.5x10^-14
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.047	[0.018, 0.077]	1.5x10^-08
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.107	[0.065, 0.148]	7.2x10^-18
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.094	[0.054, 0.133]	8.8x10^-16
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Covariate-only model	R²	0.002	[-0.006, 0.010]	4.4x10^-01
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.013	[-0.005, 0.031]	6.9x10^-02
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.034	[0.005, 0.063]	2.9x10^-03
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.021	[-0.002, 0.044]	2.0x10^-02
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.013	[-0.005, 0.031]	6.8x10^-02
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.030	[0.003, 0.057]	5.4x10^-03
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.018	[-0.004, 0.039]	3.3x10^-02
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Covariate-only model	R²	0.045	[0.033, 0.058]	8.6x10^-36
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.043	[0.032, 0.055]	2.3x10^-34
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.066	[0.052, 0.080]	8.8x10^-52
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.055	[0.042, 0.069]	1.5x10^-43
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.045	[0.032, 0.057]	3.9x10^-35
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.116	[0.098, 0.134]	1.9x10^-92
Trunc.: CE in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.107	[0.090, 0.125]	9.0x10^-85
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Covariate-only model	R²	0.030	[0.027, 0.033]	1.3x10^-194
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.055	[0.050, 0.059]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.071	[0.066, 0.076]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.060	[0.055, 0.065]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.055	[0.051, 0.060]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.105	[0.100, 0.111]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.094	[0.089, 0.100]	<1.0x10^-300
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.020	[0.006, 0.034]	2.1x10^-06
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.052	[0.031, 0.074]	1.4x10^-14
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.079	[0.053, 0.104]	2.3x10^-21
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.068	[0.044, 0.092]	1.6x10^-18
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.053	[0.031, 0.075]	1.0x10^-14
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.104	[0.075, 0.133]	5.4x10^-28
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.090	[0.063, 0.117]	2.8x10^-24
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.010	[-0.004, 0.024]	1.3x10^-02
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.052	[0.021, 0.083]	9.5x10^-09
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.078	[0.041, 0.115]	1.5x10^-12
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.066	[0.031, 0.100]	1.1x10^-10
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.053	[0.022, 0.084]	8.2x10^-09
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.088	[0.049, 0.126]	5.8x10^-14
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.067	[0.033, 0.102]	6.2x10^-11
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Covariate-only model	R²	0.003	[-0.006, 0.011]	4.9x10^-01
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.004	[-0.006, 0.013]	4.3x10^-01
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.023	[-0.001, 0.047]	4.2x10^-02
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.012	[-0.006, 0.030]	1.4x10^-01
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.003	[-0.006, 0.013]	4.4x10^-01
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.022	[-0.002, 0.046]	4.7x10^-02
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.011	[-0.006, 0.028]	1.6x10^-01
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Covariate-only model	R²	0.044	[0.032, 0.056]	8.7x10^-33
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.041	[0.029, 0.052]	2.8x10^-30
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.058	[0.044, 0.071]	1.6x10^-42
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.049	[0.036, 0.061]	6.2x10^-36
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.042	[0.030, 0.053]	9.7x10^-31
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.105	[0.088, 0.123]	6.8x10^-78
Trunc.: Free Chol. in CMs and XXL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.098	[0.081, 0.115]	2.1x10^-72
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Covariate-only model	R²	0.044	[0.040, 0.048]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.047	[0.043, 0.051]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.086	[0.080, 0.091]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.079	[0.074, 0.084]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.048	[0.044, 0.052]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.135	[0.128, 0.141]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.128	[0.122, 0.134]	<1.0x10^-300
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.035	[0.017, 0.053]	4.5x10^-12
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.044	[0.024, 0.064]	7.8x10^-15
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.081	[0.055, 0.107]	1.7x10^-26
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.081	[0.055, 0.107]	2.2x10^-26
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.045	[0.025, 0.065]	3.7x10^-15
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.123	[0.092, 0.154]	5.1x10^-40
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.121	[0.091, 0.152]	1.8x10^-39
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.020	[0.000, 0.040]	1.9x10^-04
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.034	[0.008, 0.059]	1.1x10^-06
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.083	[0.045, 0.121]	1.4x10^-14
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.079	[0.042, 0.116]	6.4x10^-14
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.035	[0.009, 0.060]	8.8x10^-07
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.100	[0.059, 0.141]	1.8x10^-17
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.092	[0.053, 0.131]	4.2x10^-16
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Covariate-only model	R²	0.011	[-0.006, 0.027]	5.8x10^-02
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.008	[-0.006, 0.023]	9.2x10^-02
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.035	[0.005, 0.064]	6.0x10^-04
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.024	[-0.001, 0.048]	4.7x10^-03
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.009	[-0.006, 0.024]	8.4x10^-02
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.044	[0.011, 0.076]	1.1x10^-04
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.032	[0.004, 0.060]	1.0x10^-03
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Covariate-only model	R²	0.059	[0.045, 0.072]	2.0x10^-51
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.040	[0.029, 0.052]	1.6x10^-35
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.072	[0.057, 0.087]	8.9x10^-63
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.067	[0.053, 0.082]	5.5x10^-59
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.041	[0.030, 0.053]	1.7x10^-36
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.133	[0.114, 0.151]	3.0x10^-118
Trunc.: PLs in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.128	[0.109, 0.147]	8.0x10^-114
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Covariate-only model	R²	0.034	[0.031, 0.038]	8.8x10^-245
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Genotype-only model	R²	0.052	[0.047, 0.056]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Genotype-only model	R²	0.078	[0.073, 0.083]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Genotype-only model	R²	0.069	[0.064, 0.074]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	White British	Full model (covariates and genotypes)	R²	0.052	[0.048, 0.057]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.116	[0.110, 0.123]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	White British	Full model (covariates and genotypes)	R²	0.108	[0.102, 0.114]	<1.0x10^-300
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Covariate-only model	R²	0.023	[0.009, 0.038]	6.2x10^-08
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Genotype-only model	R²	0.040	[0.021, 0.059]	1.2x10^-12
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Genotype-only model	R²	0.075	[0.050, 0.101]	8.0x10^-23
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Genotype-only model	R²	0.081	[0.055, 0.107]	1.7x10^-24
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	non-British White	Full model (covariates and genotypes)	R²	0.040	[0.021, 0.060]	9.0x10^-13
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.105	[0.076, 0.134]	1.3x10^-31
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	non-British White	Full model (covariates and genotypes)	R²	0.109	[0.080, 0.138]	7.4x10^-33
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Covariate-only model	R²	0.014	[-0.003, 0.031]	2.3x10^-03
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Genotype-only model	R²	0.058	[0.026, 0.091]	4.2x10^-10
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Genotype-only model	R²	0.079	[0.042, 0.116]	2.5x10^-13
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Genotype-only model	R²	0.071	[0.035, 0.106]	4.9x10^-12
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	South Asian	Full model (covariates and genotypes)	R²	0.059	[0.026, 0.091]	3.6x10^-10
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.093	[0.053, 0.132]	2.0x10^-15
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	South Asian	Full model (covariates and genotypes)	R²	0.078	[0.042, 0.115]	3.2x10^-13
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Covariate-only model	R²	0.003	[-0.006, 0.012]	3.7x10^-01
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Genotype-only model	R²	0.009	[-0.006, 0.025]	1.2x10^-01
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Genotype-only model	R²	0.027	[0.001, 0.053]	7.5x10^-03
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Genotype-only model	R²	0.004	[-0.006, 0.015]	2.9x10^-01
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	African	Full model (covariates and genotypes)	R²	0.009	[-0.006, 0.025]	1.2x10^-01
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.026	[0.000, 0.051]	9.0x10^-03
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	African	Full model (covariates and genotypes)	R²	0.007	[-0.007, 0.021]	1.7x10^-01
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Covariate-only model	R²	0.046	[0.033, 0.058]	3.1x10^-37
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Genotype-only model	R²	0.047	[0.035, 0.060]	9.4x10^-39
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Genotype-only model	R²	0.069	[0.054, 0.083]	6.7x10^-56
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Genotype-only model	R²	0.060	[0.046, 0.073]	1.4x10^-48
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	BLQ (binarized at BLQ threshold)	Others	Full model (covariates and genotypes)	R²	0.048	[0.036, 0.060]	3.6x10^-39
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Original (incl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.118	[0.100, 0.136]	4.8x10^-97
Trunc.: Free Chol. in XL VLDL	Truncated (excl. BLQ measurements)	Truncated (excl. BLQ measurements)	Others	Full model (covariates and genotypes)	R²	0.110	[0.092, 0.128]	2.9x10^-90

The predictive performance (R²), its 95% confidence interval (CI), and statistical significance (P-value) are shown for each population in UK Biobank in the held-out test set. The "model" column indicates whether the predictive performance is from the covariate-terms alone (covariate-only model), PGS terms alone (Genotype-only model), or the full model containing both PGS and covariate terms. We used the following sets of covariates in our analysis: age, sex, age², age*sex, Townsend deprivation index, and genotype PCs (PC1-PC18). Please refer to our publication for a more detailed description of the methods.

Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags

Tanigawa and Kellis. Am J Hum Genet. (2024).

Predictive performance

Predictive performance of inclusive PGS model in the hMG study

References